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For example, the glioma-toxic impact of temozolomide (TMZ) can be potentiated by xCT inhibitors, such as erastin, thus enhancing the efficacy of TMZ (87)

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Glucose-6-phosphate produced from glucose can be oxidized by glucose-6-phosphate dehydrogenase to generate NADPH and ribose-5-phosphate, necessary for nucleotide synthesis

Construction of Adenovirus and Gene Knockdown Study To construct adenoviral vectors expressing short hairpin interfering RNAs (shRNAs) against pig GPX4 or SELS, three short hairpin oligonucleotides and complementary strands were designed to target pig GPX4 and SELS, respectively

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